Compositions Containing Volatile Solvents

ABSTRACT

According to the present invention there is provided a use of a cyclic oligosaccharide for delaying the release of a volatile solvent from a composition, preferably a cosmetic composition, which comprises at least 50% volatile solvent. 
     There is also provided a use of a cyclic oligosaccharide for reducing the initial harsh solvent odour impact, for example ethanolic/alcoholic odour impact of alcoholic or hydro-alcoholic compositions.

FIELD OF THE INVENTION

The present invention relates to use of cyclic oligosaccharides in abroad range of volatile solvent containing compositions, and inparticular in cosmetic compositions, and more particularly in fragrancecompositions, comprising at least 50% volatile solvent, to delay therelease of volatile solvents from the compositions.

BACKGROUND TO THE INVENTION

It has long been a feature of many types of compositions, includingcosmetic compositions and those of other consumer products, that theycomprise volatile solvents, often for the purpose, among others, ofsolubilising ingredients, for example perfume oils, within thecomposition. The presence of perfume oils within such cosmeticcompositions is useful to mask unpleasant odours and to improve consumeracceptance of the composition through delivering a pleasant smell.Indeed, the sole purpose of some cosmetic compositions is theapplication of a pleasant odour to human or animal skin, hair, or othersuitable substrates, by use of these perfume oils. However, for the mostpart, upon application of such a cosmetic composition containing avolatile solvent, in conjunction with a fragrance, there occurs aninitial rapid evaporation of the volatile solvent. This results in aharsh, solvent odour, for example alcoholic odour, which can mask thefragrant impact and reduce consumer acceptance.

Although many attempts have been made to alter the volatility profilesof ingredients within compositions, and particularly within cosmeticcompositions, containing volatile solvents, to date, these have mainlyfocused on altering the volatility profiles of the fragrant materialsthemselves. For example, it has been suggested that the addition ofcyclic oligosaccharides to such cosmetic compositions can alter thevolatility profile of the perfume oils giving a longer lasting effect tothe fragrance of the cosmetic composition. Previous prior art in thisarea includes JP-A-50/63126 which discloses the use of perfume andcyclodextrin complexes for use in bath preparations; JP-A-7/241333 whichdiscloses a long-lasting room deodorising composition containing afragrance and cyclodextrin and U.S. Pat. No. 5,238,915 which disclosespH dependent perfume oil/cyclodextrin complexes within aromaticcompositions.

It is now desired to alter the volatility profile of the solventsthemselves within cosmetic compositions to, for example, delay therelease of the solvent and to reduce the initial harsh solvent odourimpact, for example alcoholic/ethanolic. Although some of the prior artcited above discloses compositions that contain cyclic oligosaccharidescombined with volatile solvents within a cosmetic composition, theydisclose only the durative effects that the addition of the cyclicoligosaccharide has on the release of the fragrance without specificallydisclosing any affect that the cyclic oligosaccharide has on thevolatility profile of the volatile solvent itself.

Surprisingly, it has now been found that cyclic oligosaccharides can beused within compositions, particularly cosmetic compositions, containingat least 50% volatile solvent to delay the release of volatile solventsand also to reduce the initial harsh ethanolic/alcoholic odour impact ofan alcoholic or hydro-alcoholic cosmetic composition.

While not wishing to be bound by theory, it is believed that when cyclicoligosaccharides are added to a cosmetic composition comprising at least50%, preferably from about 50% to about 99.9%, more preferably fromabout 60% to about 95%, even more preferably from about 65% to about75%, by weight, of volatile solvent, the volatile solvent itselfcompetes with the perfume oils for complexation in the cyclicoligosaccharide cavity. This results in some “in situ complexation”between the volatile solvent and the cyclic oligosaccharide. It isbelieved that the stability profile of this cyclicoligosaccharide:volatile solvent complex is such that there is a delayin the release of the volatile solvent from the composition when appliedto a substrate. It is further believed that this results in aperceptible reduction in initial solvent release thus satisfying theconsumer desire for a reduced initial harsh solvent odour, for examplealcoholic odour, upon cosmetic composition application.

SUMMARY OF THE INVENTION

According to a first aspect of the present invention there is provided ause of a cyclic oligosaccharide within a composition, more preferably acosmetic composition, comprising at least 50% volatile solvent to delaythe release of a volatile solvent.

According to a second aspect of the present invention there is provideda use of cyclic oligosaccharides within a composition, more preferably acosmetic composition, comprising at least 50% volatile solvent to reducethe initial ethanolic/alcoholic odour impact of an alcoholic orhydro-alcoholic cosmetic composition.

All percentages herein are by weight of the composition unless otherwiseindicated. All ratios are weight ratios unless otherwise indicated.Unless otherwise indicated, all percentages, ratios and levels ofingredients referred to herein are based on the actual amount of theingredient, and do not include solvents, fillers or other materialswhich may be combined with the ingredient in commercially availableproducts.

All documents referred to herein, including all patents, all patentapplications and all articles, are hereby incorporated herein byreference in their entirety unless otherwise indicated.

DETAILED DESCRIPTION OF THE INVENTION

The present invention relates to the use of cyclic oligosaccharideswithin compositions, particularly cosmetic compositions, comprising avolatile solvent for delaying the release of the volatile solvent.

As used herein the term “to delay the release of a volatile solvent”means to slow down or inhibit the evaporation rate of said volatilesolvent from such a composition.

As used herein the term “to reduce the initial harsh ethanolic/alcoholicodour impact of an alcoholic or hydro-alcoholic cosmetic composition”means that, when the fragrance of said composition is assessed, forexample by a panel, less ethanolic or alcoholic odours can be detected.

The elements of these compositions are described in more detail below

Cyclic Oligosaccharides

An essential component of the compositions used for the presentinvention is that they comprise a cyclic oligosaccharide, or mixtures ofdifferent cyclic oligosaccharides. As used herein, the term “cyclicoligosaccharide” means a cyclic structure comprising six or moresaccharide units. Preferred for use herein are cyclic oligosaccharideshaving six, seven or eight saccharide units and mixtures thereof, morepreferably six or seven saccharide units and even more preferably sevensaccharide units. It is common in the art to abbreviate six, seven andeight membered cyclic oligosaccharides to α, β and γ respectively.

The cyclic oligosaccharide of the compositions used for the presentinvention may comprise any suitable saccharide or mixtures ofsaccharides. Examples of suitable saccharides include, but are notlimited to, glucose, fructose, mannose, galactose, maltose and mixturesthereof. However, preferred for use herein are cyclic oligosaccharidesof glucose. The preferred cyclic oligosaccharides for use herein areα-cyclodextrins or β-cyclodextrins, or mixtures thereof, and the mostpreferred cyclic oligosaccharides for use herein are β-cyclodextrins.

The cyclic oligosaccharide, or mixture of cyclic oligosaccharides, foruse herein may be substituted by any suitable substituent or mixture ofsubstituents. Herein the use of the term “mixture of substituents” meansthat two or more different suitable substituents can be substituted ontoone cyclic oligosaccharide. Suitable substituents include, but are notlimited to, alkyl groups, hydroxyalkyl groups, dihydroxyalkyl groups,carboxyalkyl groups, aryl groups, maltosyl groups, allyl groups, benzylgroups, alkanoyl groups and mixtures thereof. These substituents may besaturated or unsaturated, straight or branched chain. Preferredsubstituents include saturated and straight chain alkyl groups,hydroxyalkyl groups and mixtures thereof. Preferred alkyl andhydroxyalkyl substituents are selected from C₁-C₈ alkyl or hydroxyalkylgroups or mixtures thereof, more preferred alkyl and hydroxyalkylsubstituents are selected from C₁-C₆ alkyl or hydroxyalkyl groups ormixtures thereof, even more preferred alkyl and hydroxyalkylsubstituents are selected from C₁-C₄ alkyl or hydroxyalkyl groups andmixtures thereof. Especially preferred alkyl and hydroxyalkylsubstituents are propyl, ethyl and methyl, more especially hydroxypropyland methyl and even more preferably methyl.

The cyclic oligosaccharides of the compositions used for the presentinvention are preferably substituted only by either saturated straightchain alkyl or hydroxyalkyl substituents. Therefore, preferred examplesof cyclic oligosaccharides for use herein are methyl-α-cyclodextrins,methyl-β-cyclodextrins, hydroxypropyl-α-cyclodextrin andhydroxypropyl-β-cyclodextrins. Most preferred examples of cyclicoligosaccharides for use herein are methyl-α-cyclodextrins andmethyl-β-cyclodextrins. These are available from Wacker-Chemie GmbHHanns-Seidel-Platz 4, Munchen, DE under the tradename Alpha W6 M andBeta W7 M respectively.

Methods of modifying cyclic oligosaccharides are well known in the art.For example, see “Methods of Selective Modifications of Cyclodextrins”Chemical Reviews (1998) Vol. 98, No. 5, pp 1977-1996, Khan et al andU.S. Pat. No. 5,710,268.

In addition to preferred substituents themselves, it is also preferredthat the cyclic oligosaccharides of the compositions used for thepresent invention have an average degree of substitution of at least1.6, wherein the term “degree of substitution” means the average numberof substituents per saccharide unit. Preferred cyclic oligosaccharidesfor use herein have an average degree of substitution of less than about2.8. More preferably the cyclic oligosaccharides for use herein have anaverage degree of substitution of from about 1.7 to about 2.0. Theaverage number of substituents can be determined using common NuclearMagnetic Resonance techniques known in the art.

The cyclic oligosaccharides of the compositions used for the presentinvention are preferably soluble in both water and ethanol. As usedherein “soluble” means at least about 0.1 g of solute dissolves in 100ml of solvent, at 25° C. and 1 atm of pressure. Preferably the cyclicoligosaccharides for use herein have a solubility of at least about 1g/100 ml, at 25° C. and 1 atm of pressure.

The compositions of the present invention preferably comprise from about0.001% to about 40%, more preferably from about 0.1% to about 25%, evenmore preferably from about 1% to about 20%, especially from about 1% toabout 10%, by weight, and most especially from about 2% to about 6%, byweight, of cyclic oligosaccharide. However, a person skilled in the artwill recognise that the levels of cyclic oligosaccharides used in thepresent invention will also be dependent on the components of thecomposition and their levels, for example the solvents used or the exactfragrance oils, or combination of fragrance oils, present in thecomposition. Therefore, although the above limits are preferred, theyare not exhaustive.

Volatile Solvent

A second essential element of the compositions for use in the presentinvention is a volatile solvent, or mixture of volatile solvents,comprising from about 50% to about 99.9%, more preferably from about 60%to about 95%, even more preferably from about 65% to about 75%, byweight, of the final composition. Any volatile solvent suitable for usein the compositions can be used herein. The solvents for use herein arepreferably organic volatile solvents.

As used herein, “volatile” refers to substances with a significantamount of vapour pressure under ambient conditions, as is understood bythose in the art. The volatile solvents for use herein will preferablyhave a vapour pressure of about 2 kPa or more, more preferably about 6kPa or more at 25° C. The volatile solvents for use herein willpreferably have a boiling point under 1 atm, of less than about 150° C.,more preferably less than about 100° C., even more preferably less thanabout 90° C., even more preferably still less than about 80° C.

Preferably the volatile solvents for use herein will be safe for use ona wide range of substrates, more preferably on human or animal skin orhair. Suitable volatile solvents include, but are not limited to, thosefound in the CTFA International Cosmetic Ingredient Dictionary andHandbook, 7^(th) edition, volume 2 P1670-1672, edited by Wenninger andMcEwen (The Cosmetic, Toiletry, and Fragrance Association, Inc.,Washington, D.C., 1997). Conventionally used volatile solvents includeC₃-C₁₄ saturated and unsaturated, straight or branched chainhydrocarbons such as cyclohexane, hexane, heptane, isooctane,isopentane, pentane, toluene, xylene; halogenated alkanes such asperfluorodecalin; ethers such as dimethyl ether, diethyl ether; straightor branched chain alcohols and diols such as methanol, ethanol,propanol, isopropanol, n-butyl alcohol, t-butyl alcohol, benzyl alcohol,butoxypropanol, butylene glycol, isopentyldiol; aldehydes and ketonessuch as acetone; volatile silicones such as cyclomethicones for exampleoctamethyl cyclo tetrasiloxane and decamethyl cyclopentane siloxane;volatile siloxanes such as phenyl pentamethyl disiloxane,phenylethylpentamethyl disiloxane, hexamethyl disiloxane, methoxypropylheptamethyl cyclotetrasiloxane, chloropropyl pentamethyldisiloxane, hydroxypropyl pentamethyl disiloxane, octamethylcyclotetrasiloxane, decamethyl cyclopentasiloxane; propellants, andmixtures thereof. Preferred volatile solvents are C₁-C₄ alcohols andmixtures thereof. More preferred for use herein are C₁-C₄ straight chainor branched chain alcohols for example methanol, ethanol, propanol,isopropanol and butanol and mixtures thereof, and most preferred for useherein is ethanol.

Fragrance

An optional feature of compositions for use in the present invention isthat they comprise greater than about 0.01%, by weight, fragrancematerial. As used herein the term “fragrance” is used to indicate anyodouriferous material. Any fragrance material suitable for use incosmetic compositions may be used herein but the fragrance will mostoften be liquid at ambient temperatures. Preferably, the fragrancematerials will be present at level of from about 0.01% to about 40%,preferably from about 0.1% to about 30%, more preferably from about 2.5%to about 25%, even more preferably from about 5% to about 20% and mostpreferably from about 10% to about 15%, by weight, of total composition.

A wide variety of chemicals are known for fragrance uses, includingmaterials such as aldehydes, ketones and esters. More commonly,naturally occurring plant and animal oils and exudates comprisingcomplex mixtures of various chemical components are known for use asfragrances. The fragrance materials useful herein include pro-fragrancessuch as acetal pro-fragrances, ketal pro-fragrances, esterpro-fragrances, hydrolyzable inorganic -organic pro-fragrances andmixtures thereof. The fragrance material may be released from thepro-fragrances in a number of ways. For example, the fragrance may bereleased as a result of simple hydrolysis, or by shift in an equilibriumreaction or by a pH-change, or by enzymatic release. The fragrancesherein can be relatively simple in their compositions, comprising asingle chemical, or can comprise highly sophisticated complex mixturesof natural and synthetic chemical components, all chosen to provide anydesired odour.

Preferably the fragrance materials for use in the present invention willhave boiling points (BP) of about 500° C. or lower, more preferablyabout 400° C. or lower, even more preferably about 350° C. or lower. TheBP of many fragrance materials are given in Perfume and Flavor Chemicals(Aroma Chemicals), Steffen Arctander (1969). The ClogP value of thefragrance materials useful herein is preferably greater than about 0.1,more preferably greater than about 0.5, even more preferably greaterthan about 1.0, even more preferably still greater than about 1.2. Asused herein the term “ClogP” means the logarithm to base 10 of theoctanol/water partition coefficient. This can be readily calculated froma programme called “CLOGP” which is available from Daylight ChemicalInformation Systems Inc., Irvine Calif., USA. Octanol/water partitioncoefficients are described in more detail in U.S. Pat. No. 5,578,563.

Suitable fragrance materials can be found in U.S. Pat. No. 4,145,184,U.S. Pat. No. 4,209,417, U.S. Pat. No. 4,515,705, and U.S. Pat. No.4,152,272. Examples of fragrances useful herein include, but are notlimited to, animal fragrance such as musk oil, civet, castoreum,ambergis, plant fragrances such as nutmeg extract, cardomon extract,ginger extract, cinnamon extract, patchouli oil, geranium oil, orangeoil, mandarin oil, orange flower extract, cedarwood, vetyver, lavandin,ylang extract, tuberose extract, sandalwood oil, bergamot oil, rosemaryoil, spearmint oil, peppermint oil, lemon oil, lavender oil, citronellaoil, chamomille oil, clove oil, sage oil, neroli oil, labdanum oil,eucalyptus oil, verbena oil, mimosa extract, narcissus extract, carrotseed extract, jasmine extract, oilbanum extract, rose extract andmixtures thereof.

Other examples of suitable fragrance materials include, but are notlimited to, chemical substances such as acetophenone, adoxal, aldehydeC-12, aldehyde C-14, aldehyde C-18, allyl caprylate, ambroxan, amylacetate, dimethylindane derivatives, α-amylcinnamic aldehyde, anethole,anisaldehyde, benzaldehyde, benzyl acetate, benzyl alcohol and esterderivatives, benzyl propionate, benzyl salicylate, borneol, butylacetate, camphor, carbitol, cinnamaldehyde, cinnamyl acetate, cinnamylalcohol, cis-3-hexanol and ester derivatives, ciis-3-hexenyl methylcarbonate, citral, citronnellol ans ester derivatives, cumin aldehyde,cyclamen aldehyde, cyclo galbanate, damascones, decalactone, decanol,estragole, dihydromyrcenol, dimethyl benzyl carbinol,6,8-dimethyl-2-nonanol, dimethyl benzyl carbinyl butyrate, ethylacetate, ethyl isobutyrate, ethyl butyrate, ethyl propionate, ethylcaprylate, ethyl cinnamate, ethyl hexanoate, ethyl valerate, ethylvanillin eugenol, exaltolide, fenchone, fruity esters such as ethyl2-methyl butyrate, galaxolide, geraniol and ester derivatives, helional,2-heptonone, hexenol, α-hexylcinnamic aldehyde, hydroxycitrolnellal,indole, isoamyl acetate, isoeugenol acetate, ionones, isoeugenol,isoamyl iso-valerate, iso E super, limonene, linalool, lilial, linalylacetate, lyral majantol, mayol, melonal, menthol, p-methylacetophenone,methyl anthranilate, methyl cedrylone, methyl dihydrojasmonate, methyleugenol, methyl ionone, methyl-β-naphthyl ketone, methylphenylcarbinylacetate, mugetanol, γ-nonalactone, octanal, phenyl ethyl acetate,phenyl-acetaldehyde dimethyl acetate, phenoxyethyl isobutyrate, phenylethyl alcohol, pinenes, sandalore, santalol, stemone, thymol, terpenes,triplal, triethyl citrate, 3,3,5-trimethylcyclohaxanol, γ-undecalactone,undecenal, vanillin, veloutone, verdox and mixtures thereof.

Non-volatile Solvents

While the compositions for use in the present invention preferablycomprise a volatile solvent they may also comprise “non-volatile”solvents. Suitable non-volatile solvents include, but are not limitedto, benzyl benzoate, diethyl phthalate, isopropyl myristate, propyleneglycol, dipropylene glycol and mixtures thereof.

Water

The compositions for use in the present invention may also comprisewater. If present, the water will preferably comprise from about 0.1% toabout 40%, more preferably from about 1% to about 30%, even morepreferably from about 5% to about 20%, by weight, of total composition.

Other Optional Ingredients

The compositions for use herein can contain a variety of other optionalcomponents suitable for rendering such compositions more cosmetically,aesthetically, or otherwise, acceptable or to provide them withadditional usage benefits. Such conventional optional ingredients arewell known to those skilled in the art. These include, but are notlimited to, any cosmetically acceptable ingredients such as those foundin the CTFA International Cosmetic Ingredient Dictionary and Handbook,7^(th) edition, edited by Wenninger and McEwen (The Cosmetic, Toiletry,and Fragrance Association, Inc., Washington, D.C., 1997). As used herein“cosmetically acceptable” means a material (e.g. compound orcomposition) which is suitable for use in contact with human or animalskin, hair, or other suitable substrate as defined herein below.

There are a number of other examples of additional ingredients that aresuitable for inclusion into the present compositions. These include, butare not limited to, alcohol denaturants such as denatonium benzoate; UVstabilisers such as benzophenone-2; antioxidants such as tocopherylacetate; preservatives such as phenoxyethanol, benzyl alcohol, methylparaben, propyl paraben; dyes; pH adjusting agents such as lactic acid,citric acid, sodium citrate, succinic acid, phosphoric acid, sodiumhydroxide, sodium carbonate; deodorants and anti-microbials such asfarnesol and zinc phenolsulphonate; humectants such as glycerine; oils;skin conditioning agents such as allantoin; cooling agents such astrimethyl isopropyl butanamide and menthol; hair conditioningingredients such as panthenol, panthetine, pantotheine, panthenyl ethylether; surfactants such as sodium laueth sulphate and cocoylisothionateand combinations thereof; silicones; hair-hold polymers such as thosedescribed in WO-A-94/08557; salts in general, such as potassium acetateand sodium chloride and mixtures thereof. If present, these additionalingredients will preferably be present at a level of less than 25%, byweight, of total composition. More preferably these additionalingredients will be present at a level of less than 10%, by weight, andeven more preferably at a level of less than 5%, by weight, of the totalcomposition.

Product Forms

The compositions for use in the present invention may take any formsuitable for use, more preferably for cosmetic use. These include, butare not limited to, vapour sprays, aerosols, emulsions, solid sticks,lotions, liquids, creams, gels, sticks, ointments, pastes, mousses andcosmetics (e.g., solid, semi-solid or liquid make-up, includingfoundations). Preferably the compositions for use in the presentinvention take the form of a vapour spray.

The compositions for use in the present invention will preferablycomprise a cosmetically acceptable carrier. The phrase “cosmeticallyacceptable carrier”, as used herein, means one or more compatible solidor liquid fillers, diluents, extenders and the like, which arecosmetically acceptable as defined herein above. There term“compatible”, as used herein, means that the components of thecompositions of this invention are capable of being combined with theprimary actives of the present invention, and with each other, in amanner such that there is no interaction which would substantiallyreduce the efficacy of the composition under ordinary use situations.The type of carrier utilised in the present invention depends of thetype of product desired and may comprise, but are not limited to,solutions, aerosols, emulsions (including oil-in-water or water-in-oil),gels, solids and liposomes.

Methods of Use

The present invention preferably relates to the use of a cyclicoligosaccharide for delaying the release of a volatile solvent from acomposition, particularly a cosmetic composition, for reducing theinitial solvent odour impact, for example the ethanolic/alcoholic odourimpact from a alcoholic or hydro-alcoholic cosmetic composition. Thecosmetic composition itself is preferably used for providing fragranceto a suitable substrate. As used herein the term “suitable substrate”means any surface to which the present composition may be appliedwithout an unduly adverse effect. Suitable substrates include, but arenot limited to, human or animal skin or hair, or fabrics. Preferably theuse of the present composition is likely application to skin or hair,especially skin.

Other uses for the present invention may include, but are not limitedto, compositions outside of the scope of cosmetic compositions. Examplesof such compositions include room fragrances, deodorisers for animals orotherwise, home and fabric care products such as furniture polishes,home improvement products such as paints and other spray products suchas inhalers and nasal sprays.

The preferred cosmetic compositions of the present invention may be usedin a conventional manner for fragrancing a suitable substrate. Aneffective amount of the composition, typically from about 1 μl to about1000 μl, preferably from about 10 μl to about 250 μl more preferablyfrom about 25 μl to about 100 μl is applied to the substrate. Thecomposition may be applied by hand but is preferably applied utilising avaporiser. Preferably, the composition is then left to dry.

EXAMPLES

The following examples further illustrate the preferred embodimentswithin the scope of the present invention. These examples are givensolely for the purposes of illustration and are not to be construed asimitations of the present invention as many variations of the inventionare possible without departing from its spirit or scope. Unlessotherwise indicated, all ingredients are expressed on a weightpercentage of the active ingredient.

Examples I-III

I (% wt) (comparative) II (% wt) III (% wt) Cyclic Oligosaccharide¹ 0 510 Ethanol 100 95 90 ¹Beta W7 M1.8 available from Wacker-Chemie GmbH,Hanns-Seidel-Platz 4, Munchen, DE

The cyclic oligosaccharide was dissolved in ethanol at room temperaturewith stiffing.

The samples were analysed at 32° C. using Thermo Gravimetric Analysiswhich recorded the release rate of the volatile solvent over a period oftime. The results show that samples containing a cyclic oligosaccharidehave a delayed release profile of the volatile solvent compared to thecontrol sample after 10 minutes.

% volatile Solvent Amount of volatile solvent remaining Remainingrelative to amount of volatile solvent Example after 10 mins remainingin Eg I I  7.26 ± 3.35 1 II 14.93 ± 1.34 2.1 III 28.61 ± 1.25 3.9

Examples IV-V

IV (% wt) V (% wt) Cyclic Oligosaccharide² 5 10 Ethanol 95 90 ²Alpha W6M available from Wacker-Chemie GmbH, Hanns-Seidel-Platz 4, Munchen, DE

The cyclic oligosaccharide was dissolved in ethanol at room temperaturewith stirring and the release rate of the volatile solvent was measuredas described for Examples I-III. Again the results show that samplescontaining a cyclic oligosaccharide have a delayed release profile ofthe volatile solvent compared to the control sample after 10 minutes.

% volatile Solvent Amount of volatile solvent remaining Remainingrelative to amount of volatile solvent Example after 10 mins remainingin Eg I I  7.26 ± 3.35 1 IV 19.56 ± 2.62 2.7 V 21.92 ± 0.82 3.0

Examples VI-VIII

VI (% wt) VII (% wt) VIII (% wt) Fragrance 10 12.5 15 CyclicOligosaccharide² 2.5 5 10 Ethanol 71.75 69.5 63.5 Deionised Water 15.7513 11.5 ²Beta W7 M1.8 available from Wacker-Chemie GmbH,Hanns-Seidel-Platz 4, Munchen, DE

The cyclic oligosaccharide was dissolved in ethanol at room temperaturewith stirring. Then the fragrance and water were added with stirring.

Examples IX-XI

IX (% wt) X (% wt) XI (% wt) Fragrance 3 2.5 3 Cyclic 2 5 6Oligosaccharide² Zinc phenolsulphonate 2 1 2 Dipropylene Glycol 30.514.5 17 Isopropyl myristate 1.5 7 7 Ethanol 61 70 65 ²Beta W7 M1.8available from Wacker-Chemie GmbH, Hanns-Seidel-Platz 4, Munchen, DE

The zinc phenolsulphonate is stirred into the ethanol until fullydissolved. Then the dipropylene glycol is added with stiffing. Next theisopropyl myristate, then the cyclic oligosaccharide and then thefragrance are all added with stiffing. For an aerosol deodorant apropellant such as propane butane (CAP 40®) can be added to ExamplesIX-XI according to standard industry practice.

When examples II, III, IV-XI were applied to the skin they were found tohave found to have a delayed volatile solvent release profile and alsoto have a reduced initial ethanolic/alcoholic odour impact.

1. A composition comprising: i) from about 2.5% to about 10%, by weight,of one or more C₁-C₈ alkyl-substituted cyclic oligosaccharide having anaverage degree of substitution from 1.6 to about 2.8; ii) greater thanabout 0.01% to about 15%, by weight, of a fragrance; iii) a volatilesolvent; iv) water; and v) an aerosol propellant.
 2. The composition ofclaim 1, wherein each of the one or more C₁-C₈ alkyl-substituted cyclicoligosaccharide is selected from the group consisting ofmethyl-α-cyclodextrins, methyl-β-cyclodextrins, and mixtures thereof. 3.The composition of claim 1, wherein the one or more C₁-C₈alkyl-substituted cyclic oligosaccharide consists of a mixture ofmethyl-α-cyclodextrins and methyl-β-cyclodextrins.
 4. The composition ofclaim 1, wherein the one or more C₁-C₈ alkyl-substituted cyclicoligosaccharide consists of methyl-α-cyclodextrins.
 5. The compositionof claim 1, wherein the one or more C₁-C₈ alkyl-substituted cyclicoligosaccharide consists of methyl-β-cyclodextrins.
 6. The compositionof claim 1, wherein the one or more C₁-C₈ alkyl-substituted cyclicoligosaccharide has an average degree of substitution from about 1.7 toabout 2.0.
 7. The composition of claim 1, wherein the one or more C₁-C₈alkyl-substituted cyclic oligosaccharide has an average degree ofsubstitution of 1.8.
 8. The composition of claim 1 wherein said volatilesolvent is selected from C₁-C₄ alkyl alcohols and mixtures thereof. 9.The composition of claim 1 wherein said volatile solvent comprisesethanol.